Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no therapies are aimed at the underlying mechanisms that enable this progr
This book covers important biological, immunological, and molecular information essential for understanding the rationale and results of experiments and clinica
Cell migration is a highly complex process which involves several compartments of the cell, including surface receptors, signalling elements and the cytoskeleto
Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines t
This book examines the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of th