Dietary restriction uniquely and robustly increases maximum lifespan and greatly reduces age-related diseases in many species, including yeast, flies, nematodes
For many years, it has been known that when rats and mice are given a reduced amount of food, their life span is increased and they remain healthy and vigorous
Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible