Download or read book The Functional Consequences and Therapeutic Potential of Iron Uptake-associated Systems in Escherichia Coli written by Kaveri S. Chaturvedi and published by . This book was released on 2012 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: The proliferation of antibiotic-resistant Gram-negative strains presents the challenge of untreatable bacterial infections, underscoring the need for therapeutic approaches with new microbial targets. This dissertation identifies such targets in the iron-acquisition pathways of Gram negative bacteria, and explores previously unappreciated mechanisms by which natural products associated with these pathways act as virulence determinants.