Download or read book Evaluation of National Guidelines and Implementation of New Techniques Within the Dutch Screening Program Against Cancer of the Uterine Cervix written by Albertus Gerrit Siebers and published by . This book was released on 2009 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cervical cancer screening is most effectively performed within an organized setting with quality assurance at all levels and continuous monitoring of effects. Nationally defined guidelines help to achieve a maximal reduction in the incidence of cervical cancer at the cost of a minimal number of women exposed to the negative side-effects of screening. Monitoring and evaluation of these guidelines are an essential component of quality assurance of cervical screening. Implementation of new tests or procedures should be evidence-based and preferably evaluated with randomized trials. The aim of this thesis is to evaluate existing guidelines for follow-up management on the one hand and the accuracy of liquid-based cytology (LBC) with the ThinPrep system, a new cytological test for cervical screening on the other hand with the objective to define recommendations for improvement of the quality of the Dutch screening program. It was demonstrated that evaluation of the guidelines was useful in proposing recommendations on measures for a more effective follow-up management in the cervical screening program. Furthermore, the study on the performance of LBC in the cervical screening program showed that the relative accuracy of the ThinPrep technique is equal to that of conventional cytology. However, this technique offers other advantages that could make implementation of LBC in the cervical screening program profitable. In summary, with this thesis it has been shown that in the very rapidly changing field of cervical cancer screening, good monitoring and evaluation of every change is very important as well as careful evaluation of new technologies before they are introduced in the national screening program..