Download or read book Handbook of Transcription Factor NF-kappaB written by Sankar Ghosh and published by CRC Press. This book was released on 2006-10-20 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent evidence proving the molecular link between unchecked, chronic inflammation and cancer has implicated the transcription factor NF-kB as a key factor in both inhibiting apoptosis and promoting cell proliferation. Since its initial identification 20 years ago as a simple regulating factor in one small part of the immune response, NF-kB is prov