This method provides information on health hazard likely to arise from exposure to test substance via oral administration. The determination of sub-chronic oral
This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the p
The test substance is administered in graduated doses to several groups of males and females. Males should be dosed for a minimum of four weeks. Females should