Download or read book The Recent Advances in Human Brain Organoid System and their Applications in Disease Modeling. An Introductory Review. written by Dr.Hakim Saboowala and published by Dr.Hakim Saboowala. This book was released on 2019-03-12 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: The diseases of central nervous system (CNS) usually are of complex and diverse etiologies, and could be further complicated by variable genetic, epigenetic and environmental factors that differ among individuals. The complexity and delicacy of human brain make it challenging to recapitulate its: · Development, · Function and · Disorders. Brain organoids derived from human pluripotent stem cells (PSCs) provide a new tool to model both normal and pathological human brain, and greatly enhance our ability to study brain biology and diseases. Currently, human brain organoids are increasingly used in modeling neurological disorders and relative therapeutic discovery. An attempt has been made in this Booklet to focus on recent advances in human brain organoid system and its application in disease modeling and to discuss the limitations and future perspective of human brain organoids in modeling neurological diseases. ……. Dr. H. K. Saboowala.M.B.(Bom) M.R.S.H.(London)