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Targeted Genome Editing Using Site-Specific Nucleases
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This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of eng
The Use of CRISPR/cas9, ZFNs, TALENs in Generating Site-Specific Genome Alterations
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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers
CRISPR-Cas Systems
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CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A
Human Genome Editing
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Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more
Gene Editing
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Gene-editing technologies (e.g., ZFNs, TALENs, and CRISPRs/Cas9) have been extensively used as tools in basic research. They are further applied in manufacturin