Download or read book Volume 159: Biologically Based Methods for Cancer Risk Assessment written by CC Travis (Ed) and published by . This book was released on 1989 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Research Needs for Biologically Based Risk Assessment; Multistage Models for Cancer Risk Assessment; Understanding Multistage Carcinogenesis at the Molecular Level - Notes on Recent Progress; The Use of Enzyme-Altered Foci for Risk Assessment of Hepatocarcinogens; Pathogenic Interrelationship of Focal Lesions, Nodules, Adenomas and Carcinomas in the Multistage Evolution of Azaserine-Induced Rat Pancreas Carcinogenesis; Phenotypic Cellular Changes in Multistage Carcinogenesis; Interspecies Extrapolation; Comparative Carcinogenesis, Is There a Theoretical Approach to Interspecies Similarity; Biological Basis for Interspecies Extrapolation of Halogenated Solvents and of 1,3-Butadiene; Species Specific Inhalation Pharmacokinetics of 2-Nitropropane, Methyl Ethyl Ketone, and n-Hexane; Overview of Promotion as a Mechanism in Carcinogenesis; Hepatocarcinogenesis by Non-Genotoxic Compounds; The Role of Inhibited Intercellular Communication in Carcinogenesis - Implications for Risk Assessment From Exposure to Chemicals; Comparative Analyses of the Timing and Magnitude of Genotoxic and Nongenotoxic Cellular Effects in Urinary Bladder Carcinogenesis; Alterations in Gene Expression in Mouse Hepatocarcinogenesis; Medium Term Bioassay Models for Environmental Carcinogens - Two - Step Liver and Multi-Organ Carcinogenesis Protocols; The Use of Aldh Induction as a Carcinogenic Risk Marker in Comparison With Typical in Vitro Mutagenicity System; Expression of Inducible Cytochrome P-450 mRNAs During Promotion of Experimental Chemical Hepatocarcinogenesis; An In Vitro Approach for Interspecies Extrapolation Using Animal and Human Airway Epithelial Cell Culture; Assessment of Low-Exposure Risk from Carcinogens, Implication of the Knudson-Moolgavkar Two-Critical Mutation Theory; A Biological Data Base for Methylene Chloride Risk Assessment; Computer Simulation of Chemical Carcinogenesis; Determination of Carcinogen Exposure by Immunological Techniques; Risk Estimation for Leukemogenic Drugs.