Download or read book Drug-Resistant Epilepsies written by Philippe Kahane, Anne Berg, Wolfgang Löscher, Doug Nordli, Emilio Perucca and published by John Libbey Eurotext. This book was released on 2013-09-18 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 12 million people with epilepsy have seizures that cannot be controlled by antiepileptic drugs. The term "drug-resistance" is abundantly used in the epilepsy literature but the definitions proposed differ considerably. It is used indifferently in a number of different settings: as a criterion for selection of patients eligible for new antiepileptic drug trials, for the selection of surgical candidates, for the design of epidemiological studies, for the design of studies on quality of life, for the definition of the epileptic encephalopathies (in comparison to more benign epilepsy syndromes), to mention but a few. As a result, available studies are usually not comparable and referral to epilepsy specialists is unacceptably delayed. The volume includes several focused chapters on all issues relating to drug-resistance and offers the basis for a consensus on a clinically meaningful core definition.