Lead Generation, 2 Volume Set

Lead Generation, 2 Volume Set
Author :
Publisher : John Wiley & Sons
Total Pages : 818
Release :
ISBN-10 : 9783527333295
ISBN-13 : 3527333290
Rating : 4/5 (95 Downloads)

Book Synopsis Lead Generation, 2 Volume Set by : Jörg Holenz

Download or read book Lead Generation, 2 Volume Set written by Jörg Holenz and published by John Wiley & Sons. This book was released on 2016-06-27 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this comprehensive two-volume resource on the topic senior lead generation medicinal chemists present a coherent view of the current methods and strategies in industrial and academic lead generation. This is the first book to combine both standard and innovative approaches in comparable breadth and depth, including several recent successful lead generation case studies published here for the first time. Beginning with a general discussion of the underlying principles and strategies, individual lead generation approaches are described in detail, highlighting their strengths and weaknesses, along with all relevant bordering disciplines like e.g. target identification and validation, predictive methods, molecular recognition or lead quality matrices. Novel lead generation approaches for challenging targets like DNA-encoded library screening or chemical biology approaches are treated here side by side with established methods as high throughput and affinity screening, knowledge- or fragment-based lead generation, and collaborative approaches. Within the entire book, a very strong focus is given to highlight the application of the presented methods, so that the reader will be able to learn from real life examples. The final part of the book presents several lead generation case studies taken from different therapeutic fields, including diabetes, cardiovascular and respiratory diseases, neuroscience, infection and tropical diseases. The result is a prime knowledge resource for medicinal chemists and for every scientist involved in lead generation.


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