Download or read book OECD Guidelines for the Testing of Chemicals, Section 4 Test No. 429: Skin Sensitisation Local Lymph Node Assay written by OECD and published by OECD Publishing. This book was released on 2010-07-23 with total page 20 pages. Available in PDF, EPUB and Kindle. Book excerpt: The basic principle underlying the Local Lymph Node Assay (LLNA) in mouse is that sensitizers induce a primary proliferation of lymphocytes in the auricular lymph nodes draining the site of chemical application. This proliferation is proportional to ...