Rho Gtpases: Molecular Biology In Health And Disease

Rho Gtpases: Molecular Biology In Health And Disease
Author :
Publisher : World Scientific
Total Pages : 213
Release :
ISBN-10 : 9789813228801
ISBN-13 : 9813228806
Rating : 4/5 (01 Downloads)

Book Synopsis Rho Gtpases: Molecular Biology In Health And Disease by : Philippe Fort

Download or read book Rho Gtpases: Molecular Biology In Health And Disease written by Philippe Fort and published by World Scientific. This book was released on 2017-12-12 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rho GTPases control many aspects of cell physiology. This includes polarity, endo/exocytosis, adhesion, motility, transcriptional activation, cell cycle progression or apoptosis. In view of such pleiotropic activities, Rho-controlled signaling has proven to be of medical relevance, especially in tumorigenesis, disease-associated bone remodeling and infectiology.This book is divided into three parts. Part 1 gives an evolutionary perspective of the Rho family, its atypical members, and an overview of how Rho activity is regulated. Part 2 addresses two important aspects of multicellularity controlled by Rho-dependent pathways, namely, cell-cell interactions and mechanotransduction. It also describes how post-translational modifications control Rho activity and how this is exploited by pathogenic bacteria. Part 3 explores several examples of the variety of pathophysiological processes controlled by Rho signaling, and gives a successful example of translational research, from the inhibition of Rho activation to the development of new molecules against osteoporosis.This updated review on the biology of Rho GTPases is an essential read for molecular and cell biologists. It is also an invaluable guide to post-graduate and medical students who wish to deepen their knowledge in cell biology.


Rho Gtpases: Molecular Biology In Health And Disease Related Books

Rho Gtpases: Molecular Biology In Health And Disease
Language: en
Pages: 213
Authors: Philippe Fort
Categories: Science
Type: BOOK - Published: 2017-12-12 - Publisher: World Scientific

DOWNLOAD EBOOK

Rho GTPases control many aspects of cell physiology. This includes polarity, endo/exocytosis, adhesion, motility, transcriptional activation, cell cycle progres
Handbook of Cell Signaling
Language: en
Pages: 3188
Authors: Ralph A. Bradshaw
Categories: Science
Type: BOOK - Published: 2009-11-03 - Publisher: Academic Press

DOWNLOAD EBOOK

Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular
Molecular Biology of the Cell
Language: en
Pages: 0
Authors:
Categories: Cells
Type: BOOK - Published: 2002 - Publisher:

DOWNLOAD EBOOK

The Cytoskeleton in Health and Disease
Language: en
Pages: 395
Authors: Heide Schatten
Categories: Science
Type: BOOK - Published: 2015-08-21 - Publisher: Springer

DOWNLOAD EBOOK

This volume addresses the structural and functional roles of the cytoskeleton and its dysfunctions which often lead to disease. It provides thorough discussion
Forces in Biology - Cell and Developmental Mechanobiology and Its Implications in Disease
Language: en
Pages: 171
Authors: Selwin K. Wu
Categories: Science
Type: BOOK - Published: 2020-12-11 - Publisher: Frontiers Media SA

DOWNLOAD EBOOK